Don't forget that these are going to fail in fatigue, not from yielding.
Steel can only sustain 80,000 psi tensile in fatigue application while the yield strength can be +340,000 psi. (only 23% of the yield strength)
Aluminum does not have an endurance limit and will always fail from fatigue after xxxxxx cycles. You can design around living for xxxx million cycles, however an engine gets to millions of cycles very quickly.
I did a quickie search on "aluminum endurance limit" to show an example. It is a web site about bicycle frames, but gives the basics of what I am talking about. I apologize if you already know all of this, my intent is not to be condescending, but to share. Your comment regarding 50% yield makes me believe that you are not considering this.
http://bobbrowncycles.netfirms.com/eng.htm#section1Bottom of the page shows a stress vs number of cycles diagram. - Note that the aluminum never reaches infinity for cycles like the steel does. He has 26 ksi for some reason we use 80ksi for steel in our calcs. But the example is still sound, just not the exact numbers.

You should pick a stress level that will last for a good amount of time. Maybe 200 hours on an engine @ 7000 RPM = 200*7000*60 = 84 million / 2 (head is 1/2 erpm) = 42million cycles. Now I know people have different drive cycles, etc etc and you might not spend all day at 7000, but If I were testing this I would aim high.
For the aluminum on this particular diagram (yours will be different)
42 million cycles = (42 * 10^6 ) occurs ~ 25 KSI it is a log scale btw just not shown. So this would be your design strength for a 200 hour race engine. And that has no margin for safety factor, and does not really consider the full range stress.
Safety factors for fatigue have a range stress and a peak stress component contribution.
So basically be careful with aluminum in high cycle fatigue applications. If you change them out every season, or only put 2 hours on a year it's another animal.